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In invertebrates, Caenorhabditis elegans protein skinhead-1 (SKN-1) has significant homology with Nrf2 and binds to an ARE-like element to regulate oxidative stress–related genes (80)

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The estimated values of 4.0, 4.5, and 5.5 micrograms per day, as well as the statement regarding its occurrence in foods of animal origin, come from [3]